granulocytes (Latin granulum = grain, ancient Greek cytos = cell) are part of the innate immune response. The plump cells belong to the white blood cells (leucocytes) and contain small granules inside the cell, i.a. vesicles filled with lysozyme for the lysis (resolution) of pathogens. Initially, the formation of granulocytes from myeloid progenitor cells takes place from the stem cells in the bone marrow, before the further differentiation into one of the three types of granulocytes takes place.
Granulocytes are divided into basophilic, eosinophilic and neutrophilic granulocytes. In the following, the three types are tabulated and shown in direct comparison.
Table: Types of granulocytes
|size||10 - 15 μm||10 - 15 μm||10 - 15 μm|
|function||Inflammatory reaction due to release of heparin, histamine and serotonin||Release of cytotoxic enzymes and phagocytosis||Phagocytosis of foreign pathogens|
|education||in the bone marrow|
|lifespan||1-2 weeks||1-3 weeks||1-3 days|
|Total percentage of leukocytes in the blood||1 %||5 %||50 %|