Other

Granulocyte


Definition:

granulocytes (Latin granulum = grain, ancient Greek cytos = cell) are part of the innate immune response. The plump cells belong to the white blood cells (leucocytes) and contain small granules inside the cell, i.a. vesicles filled with lysozyme for the lysis (resolution) of pathogens. Initially, the formation of granulocytes from myeloid progenitor cells takes place from the stem cells in the bone marrow, before the further differentiation into one of the three types of granulocytes takes place.
Granulocytes are divided into basophilic, eosinophilic and neutrophilic granulocytes. In the following, the three types are tabulated and shown in direct comparison.

Table: Types of granulocytes

basophil
granulocyte
eosinophilic
granulocyte
neutrophil
granulocyte
synonymbasophilseosinophilsneutrophils
coloringblueredmagenta
size10 - 15 μm10 - 15 μm10 - 15 μm
functionInflammatory reaction due to release of heparin, histamine and serotoninRelease of cytotoxic enzymes and phagocytosisPhagocytosis of foreign pathogens
educationin the bone marrow
lifespan1-2 weeks1-3 weeks1-3 days
Total percentage of leukocytes in the blood1 %5 %50 %